Search on: STROMAL INTERACTION MOLECULES 
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Descriptor English:   Stromal Interaction Molecules 
Descriptor Spanish:   Moléculas de Interacción Estromal 
Descriptor Portuguese:   Moléculas de Interação Estromal 
Tree Number:   D12.776.157.125.806
D12.776.543.875
Definition English:   Membrane-associated calcium-binding proteins that are characterized by N-terminal EF HAND MOTIFS and a STERILE ALPHA MOTIF. They function as sensors of ENDOPLASMIC RETICULUM calcium levels and translocate from the ER to the plasma membrane to activate CALCIUM CHANNELS in response to intracellular calcium depletion. 
History Note English:   2017 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   56565 
Unique Identifier:   D000071736 

Occurrence in VHL: 		 

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